NAD+ Precursor | Pittsburgh

Niagen (NR) IM Injection
in Pittsburgh.

Nicotinamide Riboside (a NAD+ precursor in cellular metabolism) delivered as a fast intramuscular injection at our South Hills studio. No IV line. No chair time. About 5 minutes.

Book Niagen IM →Compare with NAD+ IV
✓ Nurse-administered✓ ~5 min session✓ 250 / 500 / 1000mg✓ No IV required
What It Is

NR as a precursor to NAD+
in cellular energy metabolism.

Nicotinamide Riboside (NR), sold under the brand name Niagen, is a form of Vitamin B3 that plays a role in the NAD+ synthesis pathway. Your cells use NR as a building block in producing NAD+, a coenzyme involved in cellular energy metabolism.

At Signature Vitality, we offer NR as an intramuscular (IM) injection, the same delivery method as our B12, CoQ10, and Vitamin D boosters. The injection takes about 5 minutes. There is no IV line, no infusion chair, and no slow-drip requirement.

Niagen IM is a lower-friction option alongside our NAD+ IV protocols. Many clients use both as part of a personal cellular health rotation. IV for a deeper session, IM for convenient maintenance between infusions.

Quick facts about NR

Molecule class
Form of Vitamin B3 (nicotinamide)
Role in the body
Precursor in NAD+ synthesis pathway
Delivery at SV
Intramuscular injection (IM)
Session time
Approximately 5 minutes
Doses available
250mg / 500mg / 1000mg
Who administers
Registered nurse
Side by Side

Niagen IM vs. NAD+ IV:
what actually differs.

They are related, not interchangeable. Many clients use both. Here is a practical comparison without the hype.

Niagen IM

NAD+ IV

Delivery method

IM injection (intramuscular)

IV infusion (intravenous)

Session time

~5 minutes

2-6 hours depending on dose

How it works

NR converts to NAD+ inside cells

NAD+ delivered directly into bloodstream

Comfort during session

Quick injection. No IV line required.

Slow drip rate required to minimize flush sensation

Typical use case

Lower-friction maintenance; add-on to a plan

Dedicated cellular energy session or loading series

Starting price

$350 (250mg)

$250 (250mg)

Not sure which is right for you? Call us. We will help you choose.

Transparent Pricing

Niagen NR IM dosing menu.

All doses are nurse-administered IM injections. Your nurse will recommend a starting dose based on your goals and history.

Niagen NR 250mg

Entry dose, good starting point for new clients

$350

Most Popular

Niagen NR 500mg

Most popular, standard maintenance dose

$650

Niagen NR 1000mg

High-dose, nurse-directed protocol

$1,200

Book a Niagen Session →

Pricing reflects nurse-administered IM injection only. Not a subscription or package pricing.

Reported Observations Only

What clients commonly describe.

These are subjective descriptions from clients, not clinical outcomes, not guarantees, and not medical claims. Individual experience varies significantly.

Energy that feels stable

Some clients describe a sense of steadier energy through the day, not a spike, not a crash, just a feeling of running more consistently. Others notice nothing in the first session.

Cognitive freshness

A subset of clients report feeling mentally sharper or less foggy in the days following a session. This is a subjective description, not a verified cognitive outcome.

Nothing, at first

Plenty of clients feel little to nothing after session one. NR works in cellular metabolism over time. We encourage a consistent cadence before drawing conclusions.

A routine that fits

Many clients appreciate the brevity. Five minutes, no IV, no extended chair time. For people with busy schedules, the format is a practical fit.

What NR / Niagen Is NOT

Honest context.
before you book.

✓

Not FDA-approved as a treatment

Niagen (NR) is not FDA-approved for the treatment, prevention, or cure of any medical condition. We offer it as a supportive wellness service.

✓

Not a substitute for medical care

If you have a diagnosed condition, please work with your physician. Niagen IM is complementary wellness support, not a replacement for any medical protocol.

✓

Not a guaranteed outcome

Individual response to NR varies. We cannot promise specific energy levels, cognitive improvements, or any other outcome. Subjective client descriptions are just that, subjective.

✓

Not magic

Cellular metabolism is slow. One injection does not rebuild years of cellular stress. Clients who see the most value typically maintain a consistent cadence over months, not sessions.

✓

Not interchangeable with NAD+ IV

NR is a precursor: the body converts it to NAD+. Direct NAD+ IV bypasses that conversion. They are different products with different use cases.

Cellular Health Rotation

Niagen pairs naturally with these.

Many clients build a cellular health rotation that includes both Niagen IM and NAD+ IV, anchored to a structured wellness plan.

NAD+ IV Therapy
The IV cousin: direct NAD+ infusion for a deeper session or loading series
Longevity & Cellular Reset
Plan 15: biomarker-driven longevity protocol that includes NAD+ IV and optional Niagen IM
Elite Cellular Performance
Plan 16: high-dose NAD+ IV anchored plan with nurse-guided custom drips
Energy & Burnout Plan
Plan 4: 12-session mitochondrial rebuild plan that includes a Niagen IM cross-sell option
Common Questions

Frequently asked.

What is Niagen / Nicotinamide Riboside (NR)?
Niagen is a brand name for Nicotinamide Riboside (NR), a form of Vitamin B3. NR is understood to serve as a precursor to NAD+ in cellular metabolism, meaning the body uses it as a building block in the NAD+ synthesis pathway. It is not the same as direct NAD+ IV therapy.
Why choose IM injection over an oral NR supplement?
Oral NR supplements are widely available, but absorption through the digestive system varies. IM injection bypasses the gut entirely. Many clients who already take oral NR supplements add an IM session periodically as part of their cellular health rotation. We can't predict individual outcomes, but the delivery difference is well understood.
Is a Niagen IM injection comfortable?
Yes. Most clients describe it as a routine injection, similar to a flu shot. The session takes approximately 5 minutes from prep to completion. There is no IV line, no infusion chair time, and no flush reaction associated with direct NAD+ IV.
What's the difference between Niagen IM and NAD+ IV?
They are related but distinct. NAD+ IV delivers NAD+ directly into the bloodstream in a high-dose infusion session lasting 2-6 hours. Niagen IM delivers NR (a precursor) intramuscularly in about 5 minutes. Many clients use both: IV for a deeper protocol and IM for lower-friction maintenance sessions between infusions.
How do I know which dose is right for me?
Our nurse will review your intake, goals, and any current wellness plan before recommending a dose. We offer 250mg, 500mg, and 1000mg. First-time clients typically start at 250mg or 500mg.
Is Niagen FDA-approved for any condition?
No. Niagen (NR) is not FDA-approved as a treatment for any medical condition. We offer it as a wellness service: supportive cellular nutrition, not medical treatment. If you have a specific health condition, please consult your physician.
Ready? Book in Pittsburgh.

A five-minute injection.
No IV chair required.

Nurse-administered at our South Hills studio. Call us to talk through dose options, or book online and your nurse will review your intake before the session.

Book Niagen IM →See NAD+ IV Instead

Niagen (NR) is not FDA-approved for the treatment or prevention of any medical condition. This service is wellness support only. Consult your physician for any medical concerns.