NAD+ · Intensive · 1000mg

NAD+ 1000mg
in Pittsburgh.

The most-intensive nurse-directed protocol we offer. Reserved for established clients with documented 750mg tolerance and a specific longevity or recovery goal. 5 to 6 hour infusion window, full nurse attention, consult required before scheduling.

Talk to Megan to Qualify →Start at 750mg Instead
✓ $800 · 5 to 6 hours✓ No walk-ins✓ Consult required✓ Includes Replenish Drip
Who Books 1000mg

This is for you if…

You have established 750mg tolerance
Documented post-session pattern, comfortable infusion rate, and a clear pattern of what 750mg does for you. We will not escalate to 1000mg without that history.
You have a specific protocol goal
Longevity protocols agreed with Megan in advance, intensive recovery contexts after illness or surgery, or a structured stack our team is overseeing. Curiosity alone is not the reason we run this dose.
You can plan a full-day window
5 to 6 hours of nurse-supervised infusion. The longer drip window is the trade-off for the deepest dose. Bring a laptop, a book, food. This is a settle-in session.
Our team has cleared the dose
A consult conversation with Megan precedes every 1000mg booking. The site does not accept this dose as a walk-in. The consult is the gate.
Every NAD+ Session Includes

The Replenish Drip is included.

Every NAD+ dose at Signature Vitality runs alongside the Replenish Drip bundle, not a separate session, not an upsell. It runs concurrently and does not add time.

Bundled with every NAD+ dose
Glutathione
Master antioxidant; nurse-administered IV push
B-Complex
Energy-metabolism cofactors
Glutamine
Amino acid; gut + muscle support
Proline
Connective-tissue amino acid
+ 100mL fluid
Light hydration to round out the bundle
Honest Framing

What 1000mg is and isn’t.

It is an intensive protocol, not a stronger cure
A higher dose is not a stronger guarantee of any outcome. NAD+ is a coenzyme infusion. It is not FDA-approved to treat, cure, or prevent any condition. 1000mg reflects the demands of specific protocols, not a stronger claim about what NAD+ does.
It is the top of our menu, not a starting point
We do not start any client at 1000mg. The risk-reward of the deepest infusion only makes sense after a documented history with our practice at lower doses. If a different studio has offered you 1000mg as a first session, we would gently encourage you to start lower with our team.
The infusion is longer and slower
5 to 6 hours, titrated carefully. Flushing sensations are more common at this dose if the rate is pushed. The long window is what gives your nurse room to pace conservatively and pause as needed. Comfort drives the rate, not the clock.
It pairs with longevity plans, not casual visits
Plans 15 (Longevity & Cellular Reset) and 16 (Elite Cellular Performance) include 1000mg cycling as part of a broader program with biomarker labs and custom drips. If you are running this dose monthly, you should be on a plan, not paying single-session pricing.
Loading Series Option

4-day loading at 750mg.

For clients moving toward 1000mg-tier protocols, the 4-day 750mg Loading Series often comes first. It builds tolerance and a documented response pattern before any 1000mg session is scheduled. Megan can walk you through whether a Loading Series fits.

Learn About the Loading Series →
NAD+ vs. Niagen

NAD+ or Niagen? Both work.

NAD+ and Niagen both support the same cellular-energy pathway, just differently. NAD+ IV puts the active coenzyme straight into your bloodstream, a deeper, longer session. Niagen (NR) is a precursor your body converts to NAD+, given as a quick shot, an easier, more affordable way to stay topped up. Many clients use both, and your nurse can help you choose.

Learn about Niagen (NR) →
Compare Doses

Which tier is yours?

250mg
$250
2 to 3 hrs
First session / monthly maintenance
500mg
$400
3 to 4 hrs
Standard loading-series dose
750mg
$600
4 to 5 hrs
Nurse-guided escalation
1,000mg
$800
5 to 6 hrs
Advanced nurse-directed protocol
→

Consult required before 1000mg.

$800 · 5 to 6 hours · includes Replenish Drip · established clients only · consult-first.

Talk to Megan →View Longevity Plans

NAD+ IV infusion is a wellness support service and is not FDA-approved to treat, cure, or prevent any medical condition. It is not a substitute for physician care. Individual responses vary significantly. 1000mg is reserved for established clients with documented tolerance to 750mg, agreed protocol goals, and our team's clearance. We do not accept walk-in bookings at this tier. If you have an active health condition, consult your physician before booking.